Current Issue (Vol 5, May-June 2018 Issue)
 
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EDITORIAL
Blushwood berry extracts in cancer prevention: A promising future?
D. B. Nandini, Roopa S. Rao, B. S. Deepak
Full Text PDF | Abstract

ABSTRACT

Chemical extracts from the berries of Australian blushwood tree (Hylandia dockrillii) have shown to be effective in treating cancers such as melanoma and breast cancer. Blushwood berry trees are said to be exclusively seen in the rainforests of Far North Queensland, Australia. However, attempts to grow them in a greenhouse environment are being done.[1]

How to cite this article: Nandini DB, Rao RS, Deepak BS. Blushwood berry extracts in cancer prevention: A promising future? J Adv Clin Res Insights 2018;5:58.

 
ORIGINAL ARTICLE
Association of dental caries in children with black stain and non-discolored dental plaque: A microbiological study
Shruti Mutsaddi, Vijayalakshmi S. Kotrashetti, Ramakant Nayak, Smita Pattanshetty, Jagadish V. Hosmani, Deepa Babji
Full Text PDF | Abstract

ABSTRACT

Background: Dental caries is one of the most common oral diseases. Low caries has been observed in children with the presence of black stain (BS). Studies have shown that the interaction between microbiota related to extrinsic stain, cariogenic pathogens, and caries remains obscure. Very few studies have shown the prevalence rate of BS and dental caries among Indian population. Thus, the aim of the study is to estimate and compare the composition of bacteria in plaque with BS compared to the non-discolored plaque and to compare the caries experience in children with and without stains in plaque.

Materials and Methods: A total of 30 healthy children with non-discolored plaque and 30 children with BS aged between 3 and 11 years were included in the study.

Results: BS was present in 7-11 years age group. Children with BS revealed a lower overall caries experience than the children with non-discolored plaque with this correlation microbial culture showed significant lower number of cariogenic organisms Streptococcus mutans and Lactobacillus species in the BS as compared to non-discolored plaque. Higher number of Actinomyces naeslundii, Aggregatibacter actinomycetemcomitans, and Fusobacterium nucleatum indicating the good correlation between BS plaque and low caries index in Indian population.

Conclusion: The caries prevalence and microorganisms differ in BS and non-discolored plaque in children.

Keywords: Black stain, dental caries, non-discolored plaque

How to cite this article: Mutsaddi S, Kotrashetti VS, Nayak R, Pattanshetty S, Hosmani JV, Babji D. Association of dental caries in children with black stain and non-discolored dental plaque: A microbiological study. J Adv Clin Res Insights 2018; 5: 59-64.

Received 02 March 2018;

Accepted 04 April 2018

 
ORIGINAL ARTICLE
Detection of different Prevotella species from deep dentinal caries of primary teeth - A culture and biochemical study
Tanakanti Praveen, Vijayalakshmi S. Kotrashetti, Smita Pattanshetty, Jagadish V. Hosmani, Deepa Babji, Preeti Ingalagi
Full Text PDF | Abstract

ABSTRACT

Background: Oral health is a significant component of general health, with dental caries affecting a person’s ability to eat, speak, or socialize. Cariogenic bacteria show transition from predominantly facultative Gram-positive bacteria in early caries to anaerobic Gram-positive rods and cocci and Gram-negative rods in deep carious lesions. Role of Prevotella spp. in deep dentinal caries in children has been elucidated in the present study.

Materials and Methods: A total of 31 patients with age range of 6-12 years were selected. Radiographic loss of at least 50% of the total dentinal thickness was considered as deep dentinal caries. The carious dentine of selected subjects was used for culture and biochemical analysis.

Results: Of 31 samples, 15 samples showed positivity for pigmented and non-pigmented organisms in culture study using blood agar and Kanamycin-Vancomycin BA. In these 15 samples, 13 showed positivity for Prevotella spp. in biochemical analysis. Pigmented Prevotella was 42% and non-pigmented Prevotella was 6.4% in these samples.

Conclusion: This study confirms the association of Prevotella spp. in causation of deep dentinal caries in mixed dentition age group.

Keywords: Blood agar, Kanamycin-vancomycin BA, Prevotella spp.

How to cite this article: Praveen T, Kotrashetti VS, Pattanshetty S, Hosmani JV, Babji D, Ingalagi P. Detection of different Prevotella species from deep dentinal caries of primary teeth - A culture and biochemical study. J Adv Clin Res Insights 2018; 5: 65-68.

Received: 22 March 2018;

Accepted: 14 April 2018

 
ORIGINAL ARTICLE
Evaluation of serum hepcidin in oral submucous fibrosis: A noveltherapeutic approach
Tejavathi Nagaraj, H. N. Santosh
Full Text PDF | Abstract

ABSTRACT

Background: Hepcidin is an iron regulatory protein which determines the physiologic absorption of iron in the body. Oral submucous fibrosis (OSMF) is associated with iron deficiency. Alterations in the levels of hepcidin are indicative of the cause of iron deficiency in OSMF. This would greatly help in establishing the cause for iron deficiency and rationale for prescribing iron supplements in OSMF which has been long debated.

Aims and Objectives: The primary aim of this study is to find a correlation between hemoglobin and serum hepcidin in subjects with OSMF.

Materials and Methods: The study was registered with the Clinical Trial Registry of India (CTRI Number CTRI/2016/03/006761). A total of 40 subjects with varying grades of OSMF were chosen for the study by randomization. Hemoglobin and serum hepcidin were evaluated in these subjects. One-way ANOVA test was performed to find the correlation between hemoglobin percentage and hepcidin.

Results: There was a significant correlation between hemoglobin percentage and serum hepcidin in the subjects (P < 0.001). This indicates that hepcidin has an important role to play in the physiologic absorption of iron in OSMF.

Conclusion: Hepcidin can be used as an adjuvant diagnostic test in OSMF so as to assess the iron stores and thus plann for supplementation of oral or per oral iron.

Keywords: Anemia, hemoglobin, hepcidin, oral submucous fibrosis How to cite this article: Nagaraj T, Santosh HN. Evaluation of serum hepcidin in oral submucous fibrosis: A noveltherapeutic approach. J Adv Clin Res Insights 2018; 5: 69-71.

Received: 24 march 2018

Accepted: 26 April 2018

 
REVIEW ARTICLE
Plastination: Through ages
G. J. Renukaradhya, Shilpa V. S., Roopa S. Rao
Full Text PDF | Abstract

ABSTRACT

Plastination, the technique of preserving the biological tissue or whole body in its life-like state for long term, was developed in 1977 by Gunther Von Hagen. The idea was to utilize the available cadavers or samples in the best possible way to provide students of science with hands-on training into the wonders of life. The preserved tissue and body of humans and animals were also exhibited in galleries to educate the people on the workings of body tissues and organs. Even though, in early ages, the practise was viewed with serious ethical issues, the wonders of human body stated to fascinate humans and people stated donating their bodies to be platinized after their death and to be used for educational purposes. This article discusses on the basic principles and techniques of plastination and how plastination has evolved along with science. It discusses on the different synthetic polymers used as the impregnation media and the different procedures that have been developed from the basic technique. The idea is to create a dry and easy to work with specimen of a biological tissue that can do justice to the intricate and mesmerizing structure of a living tissue.

Key words: Plastination, preserving biological tissue, synthetic polymers.

How to cite this article: Renukaradhya GJ, Shilpa VS, Rao RS. Plastination: Through ages. J Adv Clin Res Insights 2018; 5: 72-74

Received: 11 April 2018;

Accepted: 26 May 2018

 
REVIEW ARTICLE
Aeronautic dentistry
Tejavathi Nagaraj, Haritma Nigam, Sita Gogula, C. K. Sumana, Swati Saxena
Full Text PDF | Abstract

ABSTRACT

Aeronautic dentistry is a developing science which studies the influence of flying and its effect on oral cavity. It has gained popularity in recent years and is frequently observed in flyers, crew members, pilots, etc. Due to the closed chamber, pressure gets accumulated in these organs causing pain, discomfort, and organ dysfunction. With proper diagnosis, the various complications can be avoided. Thus, dentist should be aware with these facts and provide a treatment inclusively. The main aim of this article is to appreciate the flying effects on dental health and to avert disorders allied with changes in atmospheric pressure.

Keywords: Aviation, crew members, dentist

How to cite this article: Nagaraj T, Nigam H, Gogula S, Sumana CK, Saxena S. Aeronautic dentistry. J Adv Clin Res Insights 2018; 5: 75-77.

Received: 27 April 2018;

Accepted: 28 May 2018

 
REVIEW ARTICLE
Investigations for diseases of the tongue: A review
Chaya M. David, L. K. Soujanya, B. K. Ramnarayan, Kanaparthi Alekhya, L K Suprith, Garima Karayat
Full Text PDF | Abstract

ABSTRACT

Tongue is a vital organ within the oral cavity that has varied function, and it may act as an index for underlying systemic diseases. The investigation of tongue disease may begin with mere clinical examination and extend to the use of few specialized tests. This article is an attempt to highlight the special investigations of tongue lesions with emphasis on clinical examination.

Keywords: Examination, investigations, tongue diseases

How to cite this article: David CM, Soujanya LK, Ramnarayan BK, Alekhya K, Suprith LK, Garima K. Investigations for diseases of the tongue: A review. J Adv Clin Res Insights 2018;5:78-83.

Received: 21 May 2018;

Accepted: 04 June 2018

 
CASE REPORT
Neonatal teeth - A case report with review of literature
Saraswathi V. Naik, Deepak S. Naik, D. B. Nandini, B. S. Deepak
Full Text PDF | Abstract

ABSTRACT

First emergence of the deciduous teeth in the oral cavity occurs at 6 months of age. Eruption of teeth at or immediately after birth is relatively rare phenomenon. Natal teeth and neonatal teeth are the teeth that are found in the oral cavity of an infant either at birth or shortly after birth within a month. The present paper reports a case of neonatal tooth and also summarizes the various characteristics associated with these conditions. It is important to know the complications and their management to avoid the discomfort for the infant.

Key words: Complications, natal teeth, neonatal teeth, precocious dentition, predeciduous teeth.

How to cite this article: Naik SV, Naik DS, Nandini DB, Deepak BS. Neonatal teeth - A case report with review of literature. J Adv Clin Res Insights 2018; 5: 84-87.

Received: 21 April 2018;

Accepted: 26 May 2018

 
CASE REPORT
A pediatric odontogenic myxoma of the maxilla: A case report and review
Preeti Singh, K. Shwetha Nambiar, Roopa S. Rao, Prathibha Shridhar, Kavitha Prasad, S. V. Sowmya, Dominic Augustine, Vanishri Charagannavar
Full Text PDF | Abstract

ABSTRACT

Odontogenic tumors represent a broad spectrum of lesions ranging from benign to malignant lesions. Benign odontogenic lesions are rare entities that are important due to their local aggressive nature and equally challenging to handle. Odontogenic myxoma (OM) in children is unusual and extremely rare. Till date, only 40 such cases have been reported in the literature with high recurrence rate between 10 and 33% with an average of 25%. We report a rare case of aggressive OM in the maxilla of a female child of 1 year and 8 months. Timely and apt histopathological diagnosis of OM enabled the surgeons to arrive at a conservative treatment plan considering esthetic and age of the child. No recurrence was noted on follow-up of the case for 6 months. The patient is kept under observation.

Keywords: Maxilla, odontogenic myxoma, pediatric

How to cite this article: Singh P, Nambiar KS, Rao RS, Shridhar P, Prasad K, Sowmya SV, Augustine D, Charagannavar V. A pediatric odontogenic myxoma of the maxilla: A case report and review. J Adv Clin Res Insights 2018; 5: 88-91.

Received: 09 April 2018

Accepted: 26 May 2018

 
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