Journal of Advanced Clinical and Research Insights

Vol. 3 | No.5 | September-October 2016 Issue

1.EDITORIAL

Odontogenic tumors- screen the unseen

Dr. Shyamala Karnam

Year:2016 | Month:September-October | Volume:3 | Number:5 | Pages No:160 | No. of Hits: 160


ABSTRACT

Odontogenic tumors are a heterogenous group of lesions arising from the odontogenic apparatus or its remnants. They may originate from the epithelial and/or ectomesenchymal odontogenic tissues, exhibiting varying degrees of inter-tissue interaction. Odontogenic tumors comprise group of tumors whose severity ranges from simple cyst like behavior to hamartomatous lesions to frank metastasizing malignancies.

How to cite this article: Karnam S. Odontogenic tumors- screen the unseen. J Adv Clin Res Insights 2016;3:160.


2.ORIGINAL ARTICLE

Spectrum of thalassemia and hemoglobinopathies in a tertiary care diagnostic center

Mohammad Shahid Iqbal, Aisha Tabassum, K. R. Chatura

Year:2016 | Month:September-October | Volume:3 | Number:5 | Pages No:161–165 | No. of Hits: 149


ABSTRACT

Context: Hemoglobinopathies and thalassemias are one of the most common genetic abnormalities prevalent in India and the Middle East.

Aim: This study was performed to identify the distribution of abnormal types of hemoglobin (Hb) in a tertiary care diagnostic laboratory.

Materials and Methods: An observational study was conducted in the Department of Hematology in a tertiary care diagnostic lab of South India to know the prevalence of hemoglobinopathies and thalassemia using high performance liquid chromatography (HPLC) as the diagnostic method.

Results: A total of 518 samples were received over a period of 6-month. All 518 samples were processed for HPLC. 407 samples were normal and 111 samples showed abnormal Hb variants. Sickle cell trait (HbS heterozygous) was diagnosed in 56 (10.8%) cases, beta thalassemia minor in 40 (7.72%) cases, and sickle cell disease (HbS homozygous) in 12 (2.5%) cases, thalassemia major in 2 (0.38%) cases and 1 (0.2%) case of hereditary persistence of fetal hemoglobin.

Conclusion: One of the best methods emerging for screening and detection of various hemoglobinopathies is HPLC. This study showed that CE-HPLC is a reliable tool in diagnosing the presence of abnormal Hb in suspected cases on routine hematology.

Keywords: Hemoglobinopathy, Sickle cell, Thalassemia

How to cite this article: Iqbal MS, Tabassum A, Chatura KR. Spectrum of thalassemia and hemoglobinopathies in a tertiary care diagnostic center. J Adv Clin Res Insights 2016;3:161-165.

Received: 03 September 2016;

Accepted: 02 October 2016


3.ORIGINAL ARTICLE

A clinical study of 341 patients with oral lichen planus in North Bengaluru population

Bhavana T. Veerabasvaiah, Tejavathi Nagaraj, Lakshmi Balraj, Haritma Nigam, I. Keerthi, R. Shruthi

Year:2016 | Month:September-October | Volume:3 | Number:5 | Pages No:166–169 | No. of Hits: 322


ABSTRACT

Background: Lichen planus is a chronic autoimmune disorder affecting the oral mucosa, skin, genital mucosa, scalp, and nails; most often seen affecting peri-menopausal women. This study provides useful data regarding the prevalence of oral lichen planus (OLP) in the North Bengaluru population including its type and gender distribution.

Aims and Objective: To provide useful data regarding the prevalence of OLP in the North Bengaluru population including its type and gender distribution (March 2013 to April 2016).

Methods: This hospital-based study recorded the cases which reported to the Department of Oral Medicine and Radiology March 2013 to April 2016. 341 cases of histologically confirmed OLP were analyzed for their gender and clinical form distribution as well as certain other parameters such as intraoral site involvement and symptoms.

Results: This study showed females being more affected by OLP with buccal mucosa being the most commonly involved site intraorally. The reticular form was the most common which was detected incidentally and erosive and atrophic forms showed maximum associated symptoms.

Conclusion: This study has highlighted the distribution of OLP among the Bengaluru population. Lichen planus is a white lesion of oral mucosa which can pose a confusing array of forms thereby mimicking other diseases. A long time follow-up is of utmost importance to detect its malignant transformation.

Keywords: Autoimmune disorder, mucocutaneous, oral lichen planus, vesiculoerosive diseases

How to cite this article: Veerabasvaiah BT, Nagaraj T, Balraj L, Nigam H, Keerthi I, Shruthi R. A clinical study of 341 patients with oral lichen planus in North Bengaluru population. J Adv Clin Res Insights 2016;3:166-169.

Received: 03 July 2016;

Revised: 20 September 2016


4.REVIEW ARTICLE

Adenomatoid odontogenic tumor: A fluctuating tumor entity

V. Keerthi Narayan, H. C. Girish, Sanjay Murgod, M. Sai Kavya, L. Nishanthi

Year:2016 | Month:September-October | Volume:3 | Number:5 | Pages No:170–172 | No. of Hits: 157 [No. of Citation: 1]


ABSTRACT

Adenomatoid odontogenic tumor (AOT) is a rare, odontogenic tumor frequently misdiagnosed; nonetheless, it has three well-documented clinicopathological variants and has been described as “two-thirds tumor” because of its occurrence in the maxilla in about two-third cases, predominantly in females of younger age, in association with tooth of uneruptive nature, and most frequently in canines. In the recent years, many cases of AOT have been reported in the uncommon sites such as mandible and posterior regions of maxilla with various histopathological presentations. The aim of the present review is to understand the various clinical, histopathological, and radiological features of AOT that have to be taken into consideration for arriving at accurate diagnosis of this so-called “fluctuating tumor.”

Keywords: Adenomatoid odontogenic tumor, benign, mandible, odontogenic adenomatoid cyst, unerupted tooth

How to cite this article: Narayan VK, Girish HC, Murgod S, Kavya MS, Nishanthi L. Adenomatoid odontogenic tumor: A fluctuating tumor entity. J Adv Clin Res Insights 2016;3:170-172.

Received: 09 August 2016;

Accepted: 22 September 2016


5.REVIEW ARTICLE

Botanicals in endodontics: A review

M. Manjunatha, Annapurna Kini

Year:2016 | Month:September-October | Volume:3 | Number:5 | Pages No:173–176 | No. of Hits: 434


ABSTRACT

Herbs and other natural products are used for various medicinal purposes. Alternative therapies are used to treat various diseases to combat side effects of allopathic medicine. Most of the herbal preparations are derived from leaves, root, seeds, and flowers. These preparations have a variety of uses in dentistry. This review article aims at a comprehensive overview of natural products used in endodontics as chelating agents, root canal irrigants, as storage media of avulsed tooth and various other uses.

Keywords: Irrigants, Morinda citrifolia, neem, propolis

How to cite this article: Manjunatha M, Kini A. Botanicals in endodontics: A review. J Adv Clin Res Insights 2016;3:173-176.

Received: 30 July 2016;

Revised: 10 September 2016


6.REVIEW ARTICLE

Ultrastructure of ameloblastoma and its variants

L. Nishanthi, Shyamala Karnam, H. C. Girish, Sanjay Murgod, Vaidhehi Narayan Nayak, Shilpa Narayan Bhat

Year:2016 | Month:September-October | Volume:3 | Number:5 | Pages No:177–182 | No. of Hits: 532


ABSTRACT

Ameloblastoma is a benign, locally aggressive, slow-growing neoplasm derived from the epithelial odontogenic tissues, which are part of the tooth-forming apparatus. It exhibits microscopic diversity which occurs either in a single pattern or in multiple patterns. There are very few reports available on ultramicroscopy regarding ameloblastoma. This paper aims at discussing and correlating the ultrastructure of ameloblastoma with the histological types for a proper understanding of its pathogenetic mechanism and thereby helping us to diagnose for a better and appropriate patient management.

Keywords: Ameloblastoma, transmission electron microscope, ultrastructure

How to cite this article: Nishanthi L, Karnam S, Girish HC, Murgod S, Nayak VN, Bhat SN. Ultrastructure of ameloblastoma and its variants. J Adv Clin Res Insights 2016;3:177-182.

Received: 12 August 2016;

Revised: 29 September 2016


7.SHORT COMMUNICATION

Rapid separation for simplified enamel reduction – Smart way to work

M. S. V. Kishore, P. Alagurajan Thivya, Rajulapudi Lakshmi Sravya, Varalakshmi Chandaveni

Year:2016 | Month:September-October | Volume:3 | Number:5 | Pages No:183–184 | No. of Hits: 362


ABSTRACT

The effort and time needed for proximal reduction makes it a tedious job for an orthodontist. Patient discomfort and gingival injuries are also reported high during inter proximal slenderization. This innovative technique uses an elliot’s separator during orthodontic tooth reduction which overcomes all these disadvantages apart from giving opportunity to preferentially reduce one tooth over other.

Keywords: Airotor reduction, Elliot’s tooth separator, interproximal reduction, rapid separation

How to cite this article: Kishore MSV, Thivya PA, Sravya RL, Chandaveni V. Rapid separation for simplified enamel reduction – Smart way to work. J Adv Clin Res Insights 2016;3:183-184.

Received: 08 August 2016;

Accepted: 22 September 2016