Journal of Advanced Clinical and Research Insights

1.CASE REPORT

An unusual presentation of aggressive central giant cell granuloma

K. Indra riyadharshini, R. Thiruneervanan, V. Mohanbabu, P. T. Ravi Kumar
[Year:2014] [Month:September-October] [Volume:1 ] [Number:2] [Pages No:53–56] [No. of Hits: 674]
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  • [Abstract]
  • [DOI : 10.15713/ins.jcri.15]

ABSTRACT

Central giant cell granuloma (CGCG) is an intraosseous lesion which occurs as an uncommon benign condition in jaws. World health organization defines this intraosseous lesions as “ lesion that contains multiple foci of hemorrhage,” consisting of cellular fibrous tissue, and there is trabeculae of woven bone. It may become aggressive leading to expansion and perforation of the cortex. Mobility and displacement of the involved teeth and root resorption are often observed. Here is a case report of an 18-year-old female patient who is diagnosed with an aggressive type of CGCG.

Keywords Central giant cell granuloma, granuloma, giant cell granuloma, giant cell lesions

2.REVIEW ARTICLE

A systematic review of various treatment modalities for oral submucous fibrosis

Anila Koneru, Santosh Hunasgi, Kaveri Hallikeri, R. Surekha, Ganesh Shreekanth Nellithady, M. Vanishree
[Year:2014] [Month:September-October] [Volume:1 ] [Number:2] [Pages No:64–72] [No. of Hits: 7373]
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  • [Abstract]
  • [DOI :  10.15713/ins.jcri.18]

ABSTRACT

Oral submucous fibrosis (OSMF) is a persistent, progressive, pre-cancerous condition of the oral mucosa, which is related with betel quid chewing habit. OSMF is strongly connected with the risk of oral cancer. Studies suggest that the dysplasia is seen in about 25% of biopsied OSMF cases. Hence, it is very important to treat and manage OSMF in early stages. The purpose of this review was to highlight various treatment modalities for OSMF with little emphasis on clinical and histopathological features of OSMF. The literature was searched using “PubMed” and electronic databases from 1994 to 2013. Key words such as OSMF and treatment, treatment modalities for OSMF and management of OSMF were used. A total of 80 articles were retrieved from 1994 to 2014. Among the retrieved articles, only 20 articles were related to medical treatment procedures and four articles reviewed the entire management of OSMF. 10 papers discussed the surgical interventions and the remaining dealt with etiopathogenesis and prevalence of the OSMF. Various types of treatment modalities include conservative methods, medical management, and invasive methods like surgical elimination of the fibrotic bands and combined therapy. Our review of the literature for treatment of OSMF yielded a spectrum of treatment modalities to manage OSMF. Recent literature proves that the combination of drugs produce effective results in the management of OSMF. However, a more extensive clinical trial is necessary to come to a final conclusion about a particular treatment modality in managing OSMF.

Keywords Conservative, combined therapy, medical, oral submucous fibrosis, surgical treatment

3.Editorial

Apical limit preparation: A paradigm in endodontics

Carlos Henrique Ribeiro Camargo
[Year:2014] [Month:September-October] [Volume:1 ] [Number:2] [Pages No:35] [No. of Hits: 517]
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  • [Abstract]
  • [DOI :  10.15713/ins.jcri.10]

ABSTRACT

Deviation between dentin canal to cementum canal and fear about touch and flush irrigants to the apical area has been for a long time a paradigm for apical preparation in many endodontic philosophies around the world. However, with the advent of nickel titanium instruments the importance and the possibility of the apical enlargement preparation improves root canal disinfection.

4.ORIGINAL ARTICLE

Assessment of the effects of staining solutions, carbamide peroxide, and mouthwashes on color stability of composite resin

Érica Crastechini, Paula de Siqueira Barbosa, Heleine Maria Chagas Rêgo, Priscila Holleben, Carlos Rocha Gomes Torres, Sérgio Eduardo de Paiva Gonçalves, Ana Paula Martins Gomes, Maria Filomena Rocha Lima Huhtala
[Year:2014] [Month:September-October] [Volume:1 ] [Number:2] [Pages No:36–41] [No. of Hits: 839]
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  • [Abstract]
  • [DOI : 10.15713/ins.jcri.11]

ABSTRACT

Objective: The aim of this study was to evaluate the effect of the four staining solutions (SS) coffee (CF), grape juice (GJ), acai berry, and green tea, on color stability of four composite resin (CR) A (Amelogen Plus/Ultradent), F (Filtek Z350 XT/3M ESPE), C (Charisma Opal/Heraeus/Kulser, and G (Grandio SO/Voco GmbH) when submitted to surface treatments (ST) using the mouthwashes (MW) Listerine Whitening (J and J); plax whitening tartar control (Colgate) and Oral B Pro-health (Oral B), and bleaching agent (BA) - 10% carbamide peroxide (CP) (Opalescence PF 10% Regular/Ultradent Products Inc.).

Materials and Methods: One hundred disks of each CR were made and distributed into subgroups: Control, MW, and BA. After ST, they were immersed into the SS (24 h). The specimens were submitted to three color measurements using a reflectance spectrophotometer (Konica Minolta).

Results: The data were submitted to the statistical analysis using the ANOVA and Tukey’s tests (P < 0.05). The results showed that after ST, the CR of Group C presented higher mean color variation (MCV). The ST that showed the highest MCV was 10% CP after submitting the specimens to the SS. Group F showed the highest MCV. The ST that showed the highest MCV was Group Oral B and the SS with the highest MCV were GJ and CF. The CR influences color stability. The MWs increase susceptibility to staining of CR. All the SS influenced color stability of CR.

Keywords Composite resin, color stability, carbamide peroxide, mouthwashes, staining solutions

5.ORIGINAL ARTICLE

Assessment and comparison of fingerprints between Kerala and Manipuri populations of India: A forensic study

Anila Koneru, Kaveri Hallikeri, Ganesh Shreekanth Nellithady, K. Rekha, Sudeendra Prabhu, K. C. Niranjan
[Year:2014] [Month:September-October] [Volume:1 ] [Number:2] [Pages No:42–45] [No. of Hits: 990]
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  • [Abstract]
  • [DOI :  10.15713/ins.jcri.12]

ABSTRACT

Background and Objective: The study of the epidermal ridges and the patterns formed by them is known as dermatoglyphics, a word coined by the anatomist Harold Cummins of Tulane University. The potential of fingerprints to determine sex and individual identification has been well exhibited and documented. However, few studies have been conducted using fingerprints for population identification. The objective of this study was to determine predominant fingerprint patterns in males and females in relation to Kerala and Manipuri population and also to compare the fingerprint patterns between these populations.

Materials and Methods: The study sample consisted of 200 subjects, which included 100 Kerala and 100 Manipuri populations in the age group of 18-21 years. Each subject was asked to press their fingertip on the stamp pad and then to the plain chart paper to transfer the fingerprint impression. All the individuals? fingerprints were identified and classified into loops, whorls, and arches. The data were statistically analyzed using the Z-test.

Results: Loops were found to be the most common fingerprint pattern among the entire study subjects. Manipuri population showed the highest frequency of loops and arches, whereas Kerala population showed more whorls. Further in our study, comparison of all fingerprint patterns between Kerala and Manipuri population revealed a significant difference for whorls and arches.

Conclusion: Difference in the fingerprint patterns between Kerala and Manipuri population exists for whorls and arches. This variation in fingerprints patterns between two populations suggests further study in associating persons to groups in more number of populations.

Keywords Fingerprints, Kerala population, Manipuri population, population identification

6.ORIGINAL ARTICLE

Microhardness of luting agents used for fiber post cementation submitted to thermo cycling

Adriana Cristina Zavanelli, José Vitor Quinelli Mazaro, Adriano T. Kian, Rosse Mary Falcón-Antenucci
[Year:2014] [Month:September-October] [Volume:1 ] [Number:2] [Pages No:46–49] [No. of Hits: 437]
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  • [Abstract]
  • [DOI : 10.15713/ins.jcri.13]

ABSTRACT

Aims and Objectives: The aim of this study was to analyze the microhardness of three resin cements used in cementing glass fiber posts in bovine incisor. The microhardness was analyzed in cervical, middle and apical thirds before and after thermocycling process.

Materials and Methods: Bovine teeth were instrumented and divided into 3 groups composed of 10 teeth each. Then, the teeth were sectioned and obturated and had their canals prepared at a depth of 12mm. Once proceeded the desobturation, the roots and glass fiber posts were prepared for adhesive cementation. After cementation, the microhardness reading was carried out. After initial reading, the samples were placed in a thermocycler and subjected to 2,000 cycles and a new microhardness reading. The data collected were subjected to analysis of variance (ANOVA) and Turkey’s test.

Results: It was observed a statistical difference among the microhardness of resin cements. However, the statistical difference of microhardness before and after thermocycling appeared only in group U-200.

Conclusion: Thermocycling reduced microhardness values in all cements evaluated in this study. The autopolymerizing cement Multilink presented the most stable microhardness mean values after thermocycling in the coronal, middle and apical thirds.

Keywords Fiber posts, microhardness, resin cement, thermocycling

7.CASE REPORT

Unicystic variant of low grade mucoepidermoid carcinoma: A rare case report

R. Surekha, Vanishree, Dinesh Singh Chauhan, Balram Singh Thakur
[Year:2014] [Month:September-October] [Volume:1 ] [Number:2] [Pages No:50–52] [No. of Hits: 1530]
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  • [Abstract]
  • [DOI :  10.15713/ins.jcri.14]

ABSTRACT

The most common malignant neoplasm of salivary gland origin is mucoepidermoid carcinoma (MEC), and it comprises of about 5-10% of all salivary gland neoplasm. It is mostly seen in major salivary glands (54%) and two third of them occurs in the parotid gland, and 46% is seen in minor salivary glands. Histo-morphological complexity of MEC has a constellation of varying amount of epidermoid cells, goblet cells, intermediate cells and mucocytes. It is graded histopathologically based on the relative proportion of cell type, cystic spaces, degree of tumor invasion, anaplasia, mitotic rates and presence or absence of necrosis into low-grade, Intermediate grade and high-grade. In the literature, several variants of MEC such as conventional, clear cell, warthin-like, sclerosing and unicystic variant have been reported. The aim of the current case report is to present a low-grade variant of unicystic MEC which is rare, but a distinctive tumor affecting the salivary gland. Till date, to the best of our knowledge only one case has been reported.

Keywords Mucoepidermoid carcinoma, salivary neoplasm, unicystic

8.CASE REPORT

Nasopalatine duct cyst: A case report

T. L. Yogesh, Akshay Shetty, Tejavathi Nagaraj, Pooja Sinha
[Year:2014] [Month:September-October] [Volume:1 ] [Number:2] [Pages No:57–60] [No. of Hits: 1503]
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  • [Abstract]
  • [DOI :  10.15713/ins.jcri.16]

ABSTRACT

Incisive canal cyst or nasopalatine duct cysts (NPDCs) are the most common non-odontogenic and developmental cysts of the maxilla. These developmental NPDC are usually asymptomatic and are discovered during routine radiological examination done for some other diagnosis. A cone-beam computed tomography (CBCT) is a valuable tool to localize a cyst within the nasopalatine canal. CBCT enables analysis of the dimension of the NPDC, analysis of the involvement of neighboring anatomical structures and assists in treatment planning. Histopathology shows non-keratinized epithelium with pseudo stratification, ciliation with neuro-vascular bundle in the capsular wall. Surgical approach with enucleation of the cyst is the mainstay in the treatment of NPDC. Since these lesions show diagnostic dilemma in clinical and radiological study, a definitive diagnosis is made by histopathology. Here we report a case of 27-year-old male patient with NPDC along with brief literature review

Keywords Anterior maxilla, nasopalatine duct cyst, non-odontogenic, trauma

9.CASE REPORT

Canalicular adenoma of the parotid gland: A case report

Kavitha Ankanathapura Puttaswamy, Jayanth Basavapatna Subramanya, Shashidara Raju, Aparna Hoskere Gopalakrishna
[Year:2014] [Month:September-October] [Volume:1 ] [Number:2] [Pages No:61–63] [No. of Hits: 1155]
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  • [Abstract]
  • [DOI : 10.15713/ins.jcri.17]

ABSTRACT

Canalicular adenomas are uncommon benign salivary gland tumors commonly affecting the minor salivary glands. Usually, 90-95% of these are reported to occur in the upper lip, followed by the buccal mucosa and palate. Here, we report a case that involved the major salivary gland as a solitary discrete mass in the lower pole of the parotid gland. The mass was surgically excised and which histopathologically revealed normal parotid tissue along an extremely cellular area enveloped by a fibrous connective tissue capsule. Cellular areas showed cells with hyperchromatic nuclei, basally placed nucleus arranged in the form of interlacing cords, small islands, all separated by thin delicate connective septa all these features characteristic of canalicular adenoma.

Keywords Benign salivary gland tumor, canalicular adenoma, parotid gland

10.REVIEW ARTICLE

Evidence-based review on anticancer effects of commonly used herbs

V. Saranya, N. Malathi
[Year:2014] [Month:September-October] [Volume:1 ] [Number:2] [Pages No:73–77] [No. of Hits: 852]
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  • [Abstract]
  • [DOI : 10.15713/ins.jcri.19]

ABSTRACT

Cancer, a disease with high morbidity and mortality rates, is a challenge to human life. The current therapeutic strategies are associated with adverse effects which necessitate alternate treatment with less adverse effects. In addition to this, cancer prevention is desirable which has led to a new concept called biochemoprevention. In this regard, medicinal properties of plants can be exploited for cancer prevention and management as they can be procured cost effectively and are less likely to produce adverse effects as they are diet derived. This article reviews the phytochemicals and evidence-based preventive and therapeutic effects of some commonly used plants with medicinal properties against cancer.

Keywords Biochemoprevention, cancer, medicinal properties of plants, phytochemicals