Journal of Advanced Clinical and Research Insights


Missed diagnosis of phyllodes tumor and its implications: A case report

K. R. Chatura, Jyothi Sajjan, C. R. Preethi
[Year:2018] [Month:January-February] [Volume:5 ] [Number:1] [Pages No:3-5] [No. of Hits: 248]
  • [PDF]
  • [Abstract]
  • [DOI : 10.15713/ins.jcri.194]


Phyllodes tumor, a fibroepithelial neoplasm, is rare and accounts for <1% of breast tumors. It is often underdiagnosed by the pathologists and undertreated by the surgeons. The pathologist has a definite role in the pre-operative diagnosis of phyllodes which is essential for planning of surgery. A consistent differentiation of phyllodes tumor from cellular fibroadenoma is often difficult. Pre-operative diagnosis by fine-needle aspiration cytology or core needle biopsy is very important to avoid reoperation because of inadequate excision or to prevent unwarranted surgery. Its heterogeneity makes phyllodes tumor, a challenge for the pathologist and the clinician. We present the case of 45-year-old female with clinical differential diagnoses of phyllodes tumor or carcinoma of right breast lump. The lack of correlation between clinical and cytological diagnosis warranted a core biopsy which was not helpful. Intraoperative frozen section was requested on the subsequent lumpectomy. Grossly, a multicystic lesion with fronds projecting into them and cysts with mucinous material was seen. Cellular imprint smears and frozen and routine histopathology sections confirmed the diagnosis of phyllodes tumor. This case aptly describes the saga of a missed pre-operative diagnosis of phyllodes tumor.

Keywords: Core needle biopsy, fine-needle aspiration cytology, frozen section, phyllodes tumor

How to cite this article: Chatura KR. Missed diagnosis of phyllodes tumor and its implications: A case report. J Adv Clin Res Insights 2018;5:3-5.

Received: 11 November 2017;

Accepted: 28 December 2017


A surgeons perspective on the treatment of cystic tumors of the jaws

Kavitha Prasad
[Year:2018] [Month:January-February] [Volume:5 ] [Number:1] [Pages No:1-2] [No. of Hits: 222]
  • [PDF]
  • [Abstract]
  • [DOI : 10.15713/ins.jcri.193]


Cystic tumors of the jaws, that is, the odontogenic keratocyst and unicystic ameloblastoma have drawn lot of attention owing to their unique characteristics and lack of agreement in their management


Twin talon cusp - A case report with review of literature

A.H. Harini Priya, Natraj Priyadarshini
[Year:2018] [Month:January-February] [Volume:5 ] [Number:1] [Pages No:6-8] [No. of Hits: 2183]
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  • [Abstract]
  • [DOI : 10.15713/ins.jcri.195]


Talons cusp is one developmental anomaly of the tooth that shows varied presentation as mentioned in the literature. The occurrence of talons cusp in the palatal aspect of the maxillary teeth has been the most common of all. These cases tend to occur due to hyperactivity of the enamel organ. The occurrence of this developmental defect in turn can lead to alteration in normal structure and function of the tooth. Hereby, we are reporting a rare occurrence of twin Talon’s cusp involving the palatal aspect of maxillary central incisor.

Keywords: Accessory cusp, dens evaginatus, maxilla, permanent incisor, talon, tooth anomaly

How to cite this article: Priya AHH, Priyadarshini N. Twin talon cusp - A case report with review of literature. J Adv Clin Res Insights 2018;5:6-8.

Received: 01 December 2017;

Accepted: 08 January 2017


Central ossifying fibroma-A unique case report

Rashmi G. S. Phulari, Kinjal Rajyaguru, Dharmesh Vasavada, Rajendrasinh Rathod
[Year:2018] [Month:January-February] [Volume:5 ] [Number:1] [Pages No:9-11] [No. of Hits: 252]
  • [PDF]
  • [Abstract]
  • [DOI : 10.15713/ins.jcri.196]


Ossifying fibroma is an osseous neoplasm occurring mainly in younger individuals with a predisposition for mandible and females are mainly affected. The tumor is not symptomatic until the expansion produces an observable swelling and little impairment. Depending on the stage of development it presents an exceedingly variable roentgenographic appearance. This neoplasm is comprised mainly of greater amount of intertwining collagen fibers, rarely organized in discrete bundles, intermixed with large amount of proliferating fibroblasts. The tumor should be removed conservatively.

Keywords: Fibro-osseous, maxilla, ossifying fibroma

How to cite this article: Phulari RGS, Rajyaguru K, Vasavada D, Rathod R. Central ossifying fibroma-A unique case report. J Adv Clin Res Insights 2018;5:9-11.

Received: 11 December 2017;

Accepted: 18 January 2017


Verrucous carcinoma of left mandibular alveolar mucosa - A case report

Tejavathi Nagaraj, H. N. Santosh, Swati Saxena, C. K. Sumana
[Year:2018] [Month:January-February] [Volume:5 ] [Number:1] [Pages No:12-14] [No. of Hits: 467]
  • [PDF]
  • [Abstract]
  • [DOI : 10.15713/ins.jcri.197]


Verrucous carcinoma is a low-grade variant of squamous cell carcinoma (SCC). It is mainly reported in head and neck region, but it has a predilection of oral cavity and larynx. Clinically, it appears as a proliferative growth along with finger-like projections or a cauliflower-like appearance which plays a significant role in its diagnosis. Most commonly, it is seen in tobacco user males. It is difficult to diagnose verrucous carcinoma histopathologically. Verrucous carcinoma is often described as a benign lesion. It has minimum aggressive potential, but transformation into SCC has been seen in long-standing cases. Thereby, early diagnosis of the lesion is very necessary, and its surgical excision is the most appropriate treatment modality of verrucous carcinoma. In this paper, we discuss a case of 78-year-old female with verrucous carcinoma of left lower alveolar mucosa.

Keywords: Oral squamous cell carcinoma, verrucous carcinoma, verrucous hyperplasia

How to cite this article: Nagaraj T, Santosh HN, Saxena S, Sumana CK. Verrucous carcinoma of left mandibular alveolar mucosa - A case report. J Adv Clin Res Insights 2018;5:12-14.

Received: 20 December 2017;

Accepted: 22 January 2017


Keratocystic odontogenic tumor

Anjani Kumar Jha, Nonitha S, Tejavathi Nagaraj, Hema Keswani, Sarvesh Vijay
[Year:2018] [Month:January-February] [Volume:5 ] [Number:1] [Pages No:15-17] [No. of Hits: 321]
  • [PDF]
  • [Abstract]
  • [DOI : 10.15713/ins.jcri.198]


Odontogenic cysts are considered as non-neoplastic benign lesions. Odontogenic keratocyst is a cystic lesion of tooth origin with an intrusive clinical behavior involving an elevated recurrence rate. It has been renamed to keratocystic odontogenic tumor (KCOT), as it explains its tumor nature which is distinguished by stratified squamous epithelium with parakeratinization and a prospective for destruction, impregnating behavior, and for the possibility for malignant transformation in the wall of the lesion. Histologic examination is necessary for diagnosis as the clinician find it difficult to manage the lesion since the true nature of the lesion is not revealed. This article is an attempt to extend an outline of a diverse strand of KCOT.

Keywords: Benign tumor, odontogenic tumor, PTCH, satellite cyst

How to cite this article: Jha AK, Nonitha S, Nagaraj T, Keswani H, Vijay S. Keratocystic odontogenic tumor. J Adv Clin Res Insights 2018;5:15-17.

Received: 29 December 2017;

Accepted: 22 February 2017


Management of resorbed mandibular ridge using neutral zone concept

Sushant A Pai, Keerthi R, Sukanya Abigail
[Year:2018] [Month:January-February] [Volume:5 ] [Number:1] [Pages No:18-20] [No. of Hits: 217]
  • [PDF]
  • [Abstract]
  • [DOI : 10.15713/ins.jcri.199]


The most common problem encountered by the complete denture patients who have severely resorbed mandibular ridge is the stability of the complete denture which poses problem for the patients in mastication which is of great importance in providing nutrition at that particular age. Patients with severely resorbed ridges, find difficulty in using the dentures during functional movements of the jaw. As the denture has to counteract the forces from the muscles of the tongue, cheeks, and lips, it becomes extremely difficult for the patient to use the denture during mandibular movements. In such situations, the rehabilitation of completely edentulous patients with resorbed ridges becomes extremely a difficult situation for a prosthodontist. Rehabilitating the patient in the present concept called the neutral zone becomes extremely important as it enhances the stability of the complete denture prosthesis which enables the patient to use the dentures with ease and comfort.

Keywords: Neutral zone, resorbed mandibular ridge, stability of the denture, stable zone, zone of minimum conflict

How to cite this article: Pai SA, Keerthi R, Abigail S. Management of resorbed mandibular ridge using neutral zone concept. J Adv Clin Res Insights 2018;5:18-20.

Received: 15 December 2017;

Accepted: 22 February 2017


Hyperpigmentation of palms - A clue to B12 deficiency

Vinoth Boopathy, Padhmini Balasubramanian
[Year:2018] [Month:January-February] [Volume:5 ] [Number:1] [Pages No:21-22] [No. of Hits: 439]
  • [PDF]
  • [Abstract]
  • [DOI : 10.15713/ins.jcri.200]


B12 deficiency anemia is commonly seen in elderly people who are pure vegetarians, especially in those who even avoids milk consumption. Hyperpigmentation of the palms is one of the common clinical manifestations of B12 deficiency, and here, we report such a case of B12 deficiency who presented with hyperpigmented palms.

Keywords: B12 deficiency, hyperpigmentation of palms, increased MCV

How to cite this article: Boopathy V, Balasubramanian P. Hyperpigmentation of palms - A clue to B12 deficiency. J Adv Clin Res Insights 2018; 5: 22-22.

Received: 15 December 2017;

Accepted: 22 February 2017